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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ddd295ede6c0e5fa3945340c0822a6d43219deeb62a8d06e85cf13215954b2' 
  AND token = 'YANPncYiwqJUp4g/oZ6e4w5aXAR3aFi3sub77S5me+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}