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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6c666da4095261956367a23ba46ba66dff0753298e0c5e6a2174a8fc224d646' 
  AND token = 'alX+xwO2u3+dEq9L+ytuRxLWlPappEoQ72ao1O6oxZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}