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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0b3508be640b78d12c483bda63bba7a1379a8cf1d2202cb4102d7cd6f5f51d' 
  AND token = 'oN08/GfXH3YlGB+t0mNnOlM/6Z1XqO+nOTPq/5FWsCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}