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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6eb53054a39166e6a525c9c18b4e1a372433ff699097c2b8056de0b56b7ee5e' 
  AND token = 'IxHldLYRIXArgkFGphiuDJ9BZbb70B+BQDeswNSMSAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}