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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '567214409d9a8d72f3800a9daffe1c5aebbddf0196957bb0028fd2073a1b5f31' 
  AND token = 'WN2TFIQe1I25EDx8RYAnyLm1IfFwFdT9JS04dfIFSJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}