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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c8a6b7b9618facfe6c43e6675b462f839d33cbef8813858510ab3eb464a0742' 
  AND token = 'PR+eY19hrbUiAzC6l+kT+YSFc4YNZDF6t3aVHh3fC54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}