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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6301b9751b58649ed518d4f1e8ff824228eb44f1f68914fe645f27cdc0275765' 
  AND token = 'ypatOBa/qH+NiW/pwVOHNyTpYVV9Ey5Vy7x7Lr9ooYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}