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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8452517a0cdfb982a51d149659847d5e5b3587109ba77c920640912d55129ac' 
  AND token = 'U9lkXb9XUNueCJmpdgycVlm7CccBGXVjiJBqHK9Qa+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}