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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '494d4725d7eb1cc0e249e58d5c7c8072f1e7cc4a0fd5da199c2bfcbf3c632737' 
  AND token = '06HFLwP9h7rfklid7U5LVprMLbieWOYdxvqydLxCF70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}