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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0eb9a9924960380293026500852a73f0c2e98b9fd0da4f8ac61a21557b848d2' 
  AND token = '3L8NoRLNAK0fbHRVox0sL+xvaKr+CEgJE8d0K/FPUy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}