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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed1daa8a41e8f0176be7a1d530cc6c7b4ec8c1b709f8047d96e4153baba355e' 
  AND token = 'Aoec7ZG6dK0G+BnisYCVIPGYY3nhvvwvfIeVwJoiX8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}