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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d47f638155ecd8e1ffd6496d032061b0ef83e2db4b27fc0881eb5da942da2b5' 
  AND token = 'dIxDS2XqU6ci4GZtkgAq40OSs6H1rDcbUqak/whB+fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}