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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c9f2af354674549829b1c233d9d3f3980498fbb7888db22f90237f75ad756ce' 
  AND token = 'vLUi6ENBldna5fa6EVTOqtQPi2Vr5xeRm8JvvBd3N74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}