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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9dff62860d9009e169e43dd30c71945e623561c659e8a7803bb9ce392902d3a' 
  AND token = '/SPLzt7Q5pWKRyR2aC2+L/BTnibeJhO5B1d4tQpYdEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}