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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51bee9f954dded361e96c16b6012851e41becc7df1063c9017e7ee38bfbc45e' 
  AND token = 'xtftd1DaPqvtxk6BgRm8NxwUrx3nCzDRc02BW/7P37U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}