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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '568106c17145aa69aeb4277cccd55935ae51563d51dafa4bfb3579596336001a' 
  AND token = 'x20tZ3z0vkoH5s0KoBYPYEZCCBwRrVFK/MF4M8JLCa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}