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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86a6e0327e602f5da45acb4cb8bb4424fd624d900d13a40859c60d39cf44067' 
  AND token = 'HwPOxFmnuxJ56D1b8NBmxg6HufLo3dQyHGinpY+xjcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}