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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd575a20cc85e9cd260fdd73573099cd05bd0023cc377eafd707b65a689d0d7f' 
  AND token = 'QvFWXrD9kFaMHiFjXgQnIeTVPDY1OoeC3+ATtEu6GBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}