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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2b9a25c434d1a3621f6b4f89e842bc71f68f20780ad070fd09ede465e66405' 
  AND token = 'f9fYdj11f+GzQnBSlqIuZX9W/Pqf4Tq0bVR+O3lse2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}