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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cabfea5e53ddf7657fbed3bdd49fc611ab55c5e8c808e203e0388d7c41e9295' 
  AND token = 'eG6xnxl1vlYpWPdHxbe49vUVWnR2H6z30x811FUzk/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}