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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e06fe835802a14356e637c3c9fe978ee870fcddd47ad77d5c428f676b4ba29ff' 
  AND token = 'dMpgUprOvqp/PBYMV6ogoUQSOlW9Pm9cuJ76MOMjnvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}