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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fad97e16b084b1b97d602e1c84646e7219e6e638e38ddeefc4efbdc42b68420' 
  AND token = 'vRh0/HAVikR9THTi1FItvdIO11vWLa1AbyShk4JPtVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}