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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3edb637760f2cb0373e9fcb37d01c4a5420f7db7a1426d428e5bce1feeb668' 
  AND token = 'oI/bb2EN8SNqoymOXmiNL1RbsyTvkh0Blw1bO80tHpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}