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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '903d75221a01e064f37d9f38712119e27daac9032d1de0bd3e4650ade302ac0c' 
  AND token = 'T/5l3+7xUrV2X7tirgxypa7k/CoFfDfVJFzCEQp/4yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}