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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4709a82c5389bfae090ea7b40a34f5790b06e5f46c40fdaae212fdc71c1568' 
  AND token = 'BT2X4XLTOm/fpaLOrQPTEvo6S85+TisYFkooUAiI3Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}