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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20437bd3c4e3b24d5c2668b506b5ef1dca897c6b8e011cd9af8bc046275b2794' 
  AND token = 'DFjG49eQcMwtEZTe2tEZgA+7L/TSLuqGT+VKt/sslb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}