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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4427109f2f524b05924f1659345a38b22fa95c8afafaa0b5d9561492664b98c' 
  AND token = 'gQQOAOz6xflwPnJQg+G0d6quwf3j9OS5ofTDP054TUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}