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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12c4d005fa39bd9aff6b5063b5fa64993163a84e724a149a6b0306b4641afbf' 
  AND token = 'QExZM1nr2DrOVv45mxIiO2OeWUmUJj7AKtJKJyjKJhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}