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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b98101cfcd76b50d2d3070d14afbe130bcc01a2a159a2fc64a5215a9b0a63f1' 
  AND token = 'DHEbC0akqUKK4ln2yrKoKTGhty34XCtG0oj8NfUvRPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}