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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '925aa6a9062a5603a8dc460258a781ec3542630bdef99d1cef3381d86377701c' 
  AND token = 'UVeX/WNJn2W19Ts/BcCauTjezEj1Xwi41Mex1S3eFUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}