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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1e923a99a2a1448d7b1608b81ff5f780f69550f1b528de56a611213e972a198' 
  AND token = 'zHAeg1tPHFvarxgYpl1rI/t6p8VySKal/IUAi4M1UVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}