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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd157295dfe8ca21ea9983d17eea54c498b08473920153f4d031b8370dbec74f6' 
  AND token = 'ire/a0bD2SkAcUlPi0VwZlIA7cmTS4SDAUpOL3PC8v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}