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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac9ebd3d1cb4261f50edd020c0ee5ef3d1f26f32465a25e458591e372e699074' 
  AND token = 'vnzUE0PZBqr28nvjW3GjF/QjKmjXT531jjpWfA3Jt6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}