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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a0c83370248e6bf34fe0fd671a719e5922f880efc2100a772944b78c4453fd' 
  AND token = 'STfYZpnp0dGYtidlbxCNuKkJMG4VGQSC/Apd65C49NM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}