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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09feded96b9f01bc0c5d7e456a592ee3721aca7ecfe0c29540a632921a8c1320' 
  AND token = 'Ls1LjW09zL8qo7HXvBv3BNjzBo/fL21HLjawAYpJtf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}