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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643b7a59efd0fe70e44caebaf3df4065f0d0027e6561167ebf09715f332f9fd2' 
  AND token = '23AfJS8jL9xVto5lhhiz9jBJwOZ48USLN8RLdJ65MSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}