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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eac489624f10b54971f2470bcdb67ad3ad1a97d2fcde453d882a8bd644484b6' 
  AND token = 'RG5KE7CHJ3ou2Jw2E1fy4Wyza6P573rPzFmIbHgpceI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}