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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14167f8b9df2a731aee6afec81b393a5962469a1b22e9fc1b093f683176f4049' 
  AND token = 'gjCP+XeNrY0jX7wVrnm3cieR6sy/4dVO1qAuBEx26zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}