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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce068cf9cb436004f317b6ef0e010e3a291f516531cc81f20c26350b8841a68' 
  AND token = 'cEr+zKrB7EddoRJot3IY+5DvCjlzdHKrOqbI4RO6R5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}