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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50388ec58a1c79745219e1e993e1ac13fcc9288ef3342d05adff19901930f809' 
  AND token = 'BjKaz4x0DYc2kb2vlw0HsGRQBvrPCwTvyq4uQBY3G+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}