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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f4148c989707ddda11e99ed98d188b0012df5607b318e67037bdd065b1478f6' 
  AND token = 'RP71AaWB8cP6Wvta/KRFYqXH4ZPGDKEgbU5Ug1BDjug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}