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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d74db5f719abd6ab9566416d15e5ecd6b1b7af63eeb7d16c1f810ecc56fec84' 
  AND token = 'I4qrgNxFzYZaHc2Dr49zNi78q9X2EDnPOFdwoqY8VzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}