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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '480341eb489fe50170e742b5e570165f0f17cfb38cc5348ae64bf19d1360e83d' 
  AND token = 'Oa0lOT6uoLpCo+r732Z9Vbh1XN/AY+WBd46EKDcEXfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}