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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5444bb8b86efed4823b69e16fef253968a0da2bb5ee511717ce1165615173c4b' 
  AND token = 'Sdli+oI+pkaVz4gVGSGoT+xxq44egxa3Usyn/SeFQ7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}