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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b279bc996ea5eacbba5205272427a579d1c4aa1e3b713a1bb04e84e99314c4' 
  AND token = 'fCpK4phaHB6PMFpUIrUyWn2dmgdVm1CVP0OGYWpCWVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}