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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '844467bf7813eb8dd9900ab9f38fe7ff94497a258d1e8f347e1d9b6aa99ea0bf' 
  AND token = '01fsbqs1ZnRA3/eTYGWwxD6XSiNapTKNRSzlnaAFBJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}