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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea63007125326d9961416663e91b3745b6f7b77d6acd8e033c69772dd3ff8d00' 
  AND token = 'D2EHN5TM83WrAMIp2r8yKPpvRyc0fDGBoyCiPupubFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}