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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4211b4984f4b32c45d59d64bd4f5d5a45cdb24763d6437fa071ad36c6951672' 
  AND token = 'cTHLrysIjaXMeo93YdlE49tusT+UImcfDYf3E4aOcWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}