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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522cb351f5a9511c131a9b7c012b3681fc18efc74228e67c74438da2d83e068b' 
  AND token = 'F0I+o5Aq6bxLaKgZeWm4w6VRGK4x4KTqRq6nxmqX31k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}