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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2485a22dd57d666907fdb2f721d7522e26f1fc4dc51fab58b73f0d2228022095' 
  AND token = 'f+d+4ys24Q43Se/d5lHg/FzcJNU1s1953XmkcRSsBPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}